Laboratory of Computational Molecular Biology
College of Life Sciences, Beijing Normal University
庞尔丽
个人自述
1973年生,汉族,山西大同人。本科毕业于北京师范大学数学系,获理学学士,后在北京师范大学生命与科学学院读取了生物信息的研究生,获理学博士, 现为北京师范大学生命科学学院教授,硕士生导师。
研究方向
主要从事生物信息学专业的研究,即利用计算机和一定的算法,来处理生物学中海量数据,主要集中在基因组和转录组和蛋白质的分析。并在数据分析的基础上,建立数据库供研究者使用。
- 蛋白质-蛋白质相互作用
- 真核生物基因组注释
- 遗传变异数据分析
- RNA-Seq 数据分析
讲授课程
- 《C语言程序设计》生命科学学院本科生课程
- 《Perl语言程序设计》生命科学学院本科生课程
- 《Perl语言程序设计》生命科学学院研究生课程
- 《Linux操作系统》生命科学学院研究生课程
论文
- Lai YT, Yeung CKL, Omland KE, Proc Natl Acad Sci U S A, 2019, 116(6):2152-2157. [Online Text] , Hao Y, Liao BY, Cao HF, Zhang BW, Yeh CF, Hung CM, Hung HY, Yang MY, Liang W, Hsu YC, Yao CT, Dong L, Lin K, Li SH(2019). Standing genetic variation as the predominant source for adaptation of a songbird.
- Song H, Lin K, Hu J,Frontiers in Plant Science, 2018, 9 :325. [Online Text] (2018). An Updated Functional Annotation of Protein-Coding Genes in the Cucumber Genome.
- Sun Y, Hou H, Song H, Lin K, Zhang Z, Hu J,BMC Plant Biol, 2018, 18(1):5. [Online Text] (2018). The comparison of alternative splicing among the multiple tissues in cucumber.
- BMC Evol Biol, 2016, 16(1):260. [Online Text] , Hao Y, Sun Y, Lin K(2016). Differential variation patterns between hubs and bottlenecks in human protein-protein interaction networks.
- Cao, H., The Plant Genome, 9(3). [Online Text] , & Lin, K.(2016). Hierarchical Map of Orthologous Genomic Regions Reconstructed from Two Closely Related Genomes: Cucumber Case Study.
- Molecular Genetics & Genomics, 1-10. [Online Text] , Wu, X., & Lin, K. (2016). Different evolutionary patterns of snps between domains and unassigned regions in human protein-coding sequences.
- Wu, X.M., PLOS ONE, doi:10.1371/journal.pone.0066745. [Online PDF] , Lin, K. and Pei, Z.M. (2013) Improving the Measurement of Semantic Similarity between Gene Ontology Terms and Gene Products: Insights from an Edge- and IC-Based Hybrid Method.
- Guo, S.G., Zhang, J.G., Sun, H.H.,..., Tan, T., Nature Genetics, doi:10.1038/ng.2470. [Online PDF] , Lin K.,..., Fei, Z.J. and Xu, Y. (2012) The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions.
- Mol. BioSyst., doi:10.1039/C1MB05364G. [Online PDF] , Tan, T. and Lin, K. (2012) Promiscuous domains: faci litating stability of the yeast protein-protein interaction network.
- Molecular BioSystems, doi: 10.1039/C0MB00038H. [Online PDF] and Lin, K. (2010) Yeast protein–protein interaction binding sites: prediction from the motif–motif, motif–domain and domain–domain levels.
- 谭涛, 庞尔丽*. 近缘物种基因组共线性片段的识别及其应用. 北京师范大学学报(自然科学版)2013(1)
- 庞尔丽. 蛋白质结构域研究进展简述. 生物学通报 2013(3)
- 庞尔丽. 蛋白质相互作用研究进展简述. 生物学通报 2012(11)
- 庞尔丽. 支架式教学与计算机程序设计语言. 计算机时代 2012(12).
- 庞尔丽. C 语言程序设计中任务驱动下的协作学习. 计算机教育 2006(5)