Zhang, Bingjun () M. S. candidate 2002 Email : zhangbj@mail.bnu.edu.cn Phone: +86-(0)10-5880 2064 Mailing Address: College of Life Sciences 502, Beijing Normal University, No.19, Xinjiekouwai Street, 100875 Beijing, China.

“The best part of your newly chosen career is that you will never have to worry about running out of things to discover.” -- Yewdell, J.W. Nat Rev Mol Cell Biol 9 , 413-416(2008).

EDUCATION Master of Science Candidate, Bioinformatics 09/2006 - Present Beijing Normal University , Beijing , P.R. China Supervisor: Dr. Deng-Ke Niu Bachelor of Science, Biotechnology 09/2002 – 07/2006 University of Science and Technology Beijing , Beijing , P.R. China RESEARCH INTERESTS - Theoretical evolutionary biology - Computational biology - Biological networks RESEARCH EXPERIENCE Graduate Research 09/2006 – Present - Tested hypotheses we proposed to study the regulation of R-loop formation by predicting potential R-loop formation sites and analyzing their correlation with cis-regulatory elements. transcriptional rate as well as newly gained introns. - Tested dosage hypothesis and imbalance hypothesis of haploinsufficient genes by analyzing variation of the extent of protein wrapping, gene structure and codon usage bias between haploinsufficient genes and over-expression genes in Saccharomyces cerevisiae. - Tested the hypotheses mentioned above by integrating clinical validated haploinsufficient/haplosufficient genes and analyzing differences of copy number variation between the two groups in Homo sapiens. - Tested hypotheses we proposed to study differences of cancer sensitivity between human and mouse by analyzing the gene expression level and expression breadth variation of homologous oncogenes, tumor suppressor genes and DNA repair genes. - Involved in research of intron loss and intron gain in the group. Undergraduate Research 09/2004 – 07/2006 - Participated in a program of biodegradation of methyl parathion, a widely used organophosphorus pesticide. Isolated and identificated a new strain, named Acinetob-acter radioresistens USTB-04, which is capable of biodegrading methyl parathion under restrictive culture conditions. - Cloned of the gene encoding trehalose-6-phosphate synthase from Porphyra y-ezoensis in silico. RESEARCH SKILLS - Programming languages: Perl, C, R - Database management: MySQL - Statistical software: SPSS - Operatings Systems: Unix/Linux, Windows TRAINING 2007 Graduate Summer School on Bioinformatics of China (GSSBC'07) 2007.07.26 - 2007.08.24 at Tsinghua University, Beijing, P.R. China Courses in Molecular Population Genetics and Evolutionary Theories. Professor Chung-I Wu, Department of Molecular Genetics, University of Chicago 2006.04.09 - 2006.04.13 at Sun Yat-sen University, Guangzhou, P.R. China Courses in Linkage, Association and QTL Mapping. Courses in Statistical Methods for Mapping Quantitative Trait Loci. Professor Zhao-Bang Zeng, Department of Statistics and Genetics, Bioinformatics Research Center, North Carolina State University 2006.04.15 - 2006.04.19 at Sun Yat-sen University, Guangzhou, P.R. China TEACHING EXPERIENCE Teaching assistant of undergraduate course Introduction to life sciences. - Assisted professor preparing materials for the course.