Laboratory of Computational Molecular Biology

College of Life Sciences, Beijing Normal University
 
 
 
 
 

 

 

Zhang, Bingjun ()

M. S. candidate 2002

Email : zhangbj@mail.bnu.edu.cn
Phone: +86-(0)10-5880 2064

Mailing Address:

College of Life Sciences 502,

Beijing Normal University,

No.19, Xinjiekouwai Street,

100875 Beijing, China.

 

The best part of your newly chosen career is that you will never have to worry about running out of things to discover.

-- Yewdell, J.W. Nat Rev Mol Cell Biol 9 , 413-416(2008).

EDUCATION

  • Master of Science Candidate, Bioinformatics

    09/2006 - Present

    Beijing Normal University , Beijing , P.R. China

    Supervisor: Dr. Deng-Ke Niu

    Bachelor of Science, Biotechnology

    09/2002 C 07/2006

    University of Science and Technology Beijing , Beijing , P.R. China

  • RESEARCH INTERESTS

    - Theoretical evolutionary biology

    - Computational biology

    - Biological networks

    RESEARCH EXPERIENCE

    • Graduate Research 09/2006 C Present

      - Tested hypotheses we proposed to study the regulation of R-loop formation by predicting potential R-loop formation sites and analyzing their correlation with cis-regulatory elements. transcriptional rate as well as newly gained introns.

      - Tested dosage hypothesis and imbalance hypothesis of haploinsufficient genes by analyzing variation of the extent of protein wrapping, gene structure and codon usage bias between haploinsufficient genes and over-expression genes in Saccharomyces cerevisiae.

      - Tested the hypotheses mentioned above by integrating clinical validated haploinsufficient/haplosufficient genes and analyzing differences of copy number variation between the two groups in Homo sapiens.

      - Tested hypotheses we proposed to study differences of cancer sensitivity between human and mouse by analyzing the gene expression level and expression breadth variation of homologous oncogenes, tumor suppressor genes and DNA repair genes.

      - Involved in research of intron loss and intron gain in the group.

    • Undergraduate Research 09/2004 C 07/2006

      - Participated in a program of biodegradation of methyl parathion, a widely used organophosphorus pesticide. Isolated and identificated a new strain, named Acinetob-acter radioresistens USTB-04, which is capable of biodegrading methyl parathion under restrictive culture conditions.

      - Cloned of the gene encoding trehalose-6-phosphate synthase from Porphyra y-ezoensis in silico.

    RESEARCH SKILLS

      - Programming languages: Perl, C, R

      - Database management: MySQL

      - Statistical software: SPSS

      - Operatings Systems: Unix/Linux, Windows

    TRAINING

    2007 Graduate Summer School on Bioinformatics of China (GSSBC'07)
    2007.07.26 - 2007.08.24 at Tsinghua University, Beijing, P.R. China

    Courses in Molecular Population Genetics and Evolutionary Theories.
    Professor Chung-I Wu, Department of Molecular Genetics, University of Chicago
    2006.04.09 - 2006.04.13 at Sun Yat-sen University, Guangzhou, P.R. China

    Courses in Linkage, Association and QTL Mapping.
    Courses in Statistical Methods for Mapping Quantitative Trait Loci.
    Professor Zhao-Bang Zeng, Department of Statistics and Genetics, Bioinformatics Research Center, North Carolina State University
    2006.04.15 - 2006.04.19 at Sun Yat-sen University, Guangzhou, P.R. China

    TEACHING EXPERIENCE

      Teaching assistant of undergraduate course Introduction to life sciences.

      - Assisted professor preparing materials for the course.

      © Laboratory of Computational Molecular Biology
    College of Life Sciences, Beijing Normal University